If you’re dealing with pain, you just want it to stop. While medications can help, some natural supplements might also provide relief. But before trying anything, it’s important to figure out what’s causing your pain.
Step One: Talk to Your Doctor
The best thing to do is check with your doctor. Explain your symptoms—what kind of pain you’re feeling, when it started, and how long it’s been going on. Once you know the cause, you can explore different ways to manage it, including physical therapy, exercise, dietary changes, and supplements.

Not all supplements work the same way for every type of pain, and some can interact with medications you’re already taking. Always check with your doctor before trying anything new.
Supplements for Back and Joint Pain
Turmeric
Turmeric, a bright yellow spice related to ginger, has powerful anti-inflammatory properties. You can cook with it, drink it as tea, or take it in capsule form.
Devil’s Claw Root
This herb may help with lower back pain and arthritis. Studies suggest taking 30-100 mg of its active ingredient, harpagoside, daily. If you have a sensitive stomach, start with a lower dose to avoid mild stomach discomfort.
Capsaicin (from Chili Peppers)
Capsaicin, the compound that gives chili peppers their heat, is often used in creams to reduce back pain. Look for a cream with 0.025%-0.075% capsaicin and apply it directly to the painful area. Capsaicin supplements may also help with digestive issues like cramps.
Comfrey
A cream made with comfrey extract may help with upper and lower back pain. Apply it three times a day—but make sure to see a doctor first to rule out any serious underlying conditions. Never take comfrey by mouth, as it can harm your liver.
Glucosamine and Chondroitin
These two compounds help form cartilage in the body. Some people find they relieve joint pain and improve movement, but research is mixed. If you try them, be patient—it may take up to four months to notice results.

Also Read: How does Sleep Affect Recovery from Physical Injuries?
Supplements for Headaches

White Willow Bark
Often called “nature’s aspirin,” white willow bark contains salicin, which helps reduce inflammation and pain. You can take it as tea or in capsule form (120-240 mg per day). Avoid high doses if you have a sensitive stomach, and don’t use it for children under 18 due to the risk of Reye’s syndrome.
Boswellia (Indian Frankincense)
This tree resin may help with cluster headaches by making them less frequent and less intense.
Caffeine
Caffeine can boost the effectiveness of pain relievers like ibuprofen and acetaminophen, especially for migraines and tension headaches. But be careful—too much caffeine or sudden withdrawal can also trigger headaches.
Feverfew and Butterbur
These herbs might help prevent and treat migraines, though more research is needed. If you get frequent migraines, it’s worth looking into.
Other Natural Remedies for Pain

Omega-3 Fatty Acids
Found in foods like fatty fish, spinach, and eggs with added omega-3s, these healthy fats reduce inflammation. If you prefer supplements, up to 3 grams of fish oil per day may help with joint pain, back pain, and menstrual cramps.
Probiotics
These beneficial bacteria support gut health and may reduce pain linked to inflammation. Try foods like yogurt (with live active cultures), kimchi, kefir, and sauerkraut, or take a probiotic supplement.

Also Read: What is the Best Over‑the‑Counter Pain Relief Cream for Joint Pain?
Supplements for Arthritis Pain

SAM-e
This man-made version of a natural compound in the body may help with arthritis symptoms. Some research suggests it works as well as certain medications. A typical dose is 200 mg three times a day.
Glucosamine and Chondroitin
If you have moderate to severe osteoarthritis, these supplements may help with pain and stiffness. However, results vary, so check with your doctor before trying them.
Boswellia
This tree resin has been shown to ease osteoarthritis and rheumatoid arthritis pain. It’s available in capsule or tablet form.
Capsaicin Cream
Applying capsaicin cream, gel, or patches three times a day may temporarily ease arthritis pain. Stop using it if it irritates your skin.
Other Options
Some other natural supplements that might help with arthritis include avocado-soybean oil blend, cat’s claw, fish oil, gamma-linolenic acid (GLA), and ginger. More research is needed, but they could be worth trying.
Supplements for Fibromyalgia

Vitamin D
Many people with fibromyalgia have low vitamin D levels, which can contribute to chronic pain. Taking a vitamin D supplement may help reduce discomfort.

Also Read: What do User Reviews Say About Popular Pain Relief Balms?
Final Thoughts
Natural supplements can be a great addition to your pain management plan, but they’re not a cure-all. The most effective approach is a combination of diet, exercise, good sleep, and stress management. Always talk to your doctor before adding supplements to your routine, especially if you’re taking other medications.
Would you like more details on any of these remedies?